1-Testosterone

1-Testosterone™ by Hi-Tech Pharmaceuticals is based upon a naturally occurring metabolite for many animals including man that has properties far different from standard testosterone in the body. 1-Testosterone™ is more of a mild hormone that will give you cleaner gains and dramatic strength increases. There are three prohormones to this compound:1-androstenedione, 1-androstenediol and 1-Androsterone aka 1-androstene-3b-ol-17-one. Of the three, only 1-androsterone is still available on the U.S. market, and this is what Hi-Tech manufactures using its proprietary Cyclosome™ Delivery system for increased bioavailability.

THE SCIENCE
In a recent study released in the Journal of Applied Physiology, the oral prohormone 1-androstene-3b-ol-17-one which converts in the liver to 1-Testosterone was as potent milligram-for-milligram to Testosterone Enanthate, the gold standard for Testosterone products. Very few dietary supplements have been subjected to a clinical study. However, the active prohormone 1-androstene-3b-ol-17-one was the subject of a clinical study at the West Texas A&M University, the California Baptist University and the University of Texas at Austin. The results showed 1-androstene-3b-ol-17-one to be significantly more powerful than it would appear structurally. The 9 males gained an average lean mass of 10.4 lbs and an increase in strength of 92.2 lbs in total load on bench/squat/deadlift. These are significant gains from a prohormone. The researchers concluded that the prohormone supplement contributed to robust improvements in muscle mass and strength in resistance trained. Although repeated studies are necessary to substantiate the efficacy of any compound, it’s safe to say that 1-androstene-3b-ol-17-one definitely packs a punch.

1-Testosterone would give you clean gains that are very dry and lean in nature. This means you won’t get a lot of bloat or estrogen activity with this prohormone. The lack of estrogen actually causes most people to stack this steroid with 4-andro or another “wet” compound. This helps potentiate the gains and increase the “comfort” of the cycle. 1-Testosterone™ will help give you clean gains that are very sustainable and help your strength go through the roof .

1-Testosterone Structure

1-Testosterone has a structure similar to testosterone but the double bond is in a different place. 1-Testosterone is a 1,2-double bond instead of a 4,5-double bond in its A ring. This slight modification means that the molecule is subject to different metabolism than standard testosterone. It cannot be converted to estrogen via aromatase nor can it be turned into DHT. This makes it a very stable molecule and resists most traditional routes of metabolism. A 2006 study determined that 1-testosterone has a high androgenic and anabolic potency even without being metabolized. 1-testosterone binds in a manner that is highly selective to the androgen receptor (AR) and has a high potency to stimulate AR-dependent transactivation. 1-Testosterone has an anabolic to androgenic ratio of 200/100, which is superior to testosterone.

With 1-Testosterone™, many users report a hardening effect and an increase in vascularity. 1-Testosterone™ appears to be best used for size gains, although it provides the user with incredible strength gains as well. 1-Testosterone™ is considered a “dry” compound which can be used during cutting phases yet because of its strength is can also be useful during a bulking phase.

With its favorable anabolic to androgenic ratio, the androgenic side effects are not too high with this compound in comparison to other steroids like testosterone. 1-Testosterone™ with its orally active prohormone 1-androstene-3b-ol-17-one is still legally available and converts to 1-testosterone in a two step process. Only Hi-Tech has the exact same dose as studied in the Texas/California study that has been compared to Testosterone Enanthate, the gold standard for Testosterone products! Try Hi-Tech's revolutionary 1-Testosterone™ for exceptionally clean muscle gains and dramatic strength increases.

Bodybuilders, fitness enthusiasts, and athletes pay attention. The muscle-building breakthrough of the 21st century is here and the results being achieved by 1-Testosterone™ has been phenomenal. 1-Testosterone™ works to create the perfect anabolic environment for unbelievable gains in lean muscle mass and strength that will not disappear when your cycle is completed!

SUGGESTED USE
As a dietary supplement, take 1 tablet in the morning and 1 tablet in the evening. Do not exceed 2 per day.

CYCLOSOME™ DELIVERY

Hi-Tech Pharmaceuticals is an Innovator in the Bodybuilding and Prohormone industry being one of the first companies to introduce many of the prohormones that have entered the marketplace over the last decade. Researchers at Hi-Tech recently developed a proprietary process called Cyclosome™ Technology. This one-of-a-kind technology brought to you by the leaders in Prohormones involves the entrapment of hydrophobic prohormones and other Testosterone boosting compounds in the form of water-soluble Prohormone–cyclodextrin (CD) complex in liposomes has been investigated as a new strategy to combine the relative advantages of CDs and liposomes into one system, namely Prohormone-in-CD-in-liposome systems called Cyclosome's™. You can think of all this in terms of a ‘Trojan Horse,’ passing through the liver unharmed and intact. As opposed to being destroyed in the liver like all other hormonal products on the market, past and present. This new Cyclosome™ technology allows the ‘Trojan Horse’ to deliver prohormones and testosterone boosters to the systemic circulation by the intestinal lymphatic route, circumventing first-pass inactivation in the liver for the very first time. Almost all previous Oral capsules and tablets manufactured to increase testosterone — including Testosterone itself — are involved in the "first pass affect" which renders the active compounds virtually useless.

Cyclosome™ Technology — the most advanced liposomal delivery technology ever developed for bioavailability is the answer to getting poorly absorbed Testosterone boosting compounds and legal prohormones into the body so they can work ! The pharmaceutical industry has embraced this cutting-edge technology in recent years and now 1-Testosterone™ will be one of the first to utilize it in a testosterone booster and anabolic agent.

For Cyclosome™ preparation, an overall understanding of the interaction between CDs and lipid Using Cycloplex Pro Hormonescomponents of liposomes is necessary for this complex. Hi-Tech has developed a Double-loading technique, which is a revolutionary strategy to prohormone release and increase prohormone-loading capacity. The Cyclosome™ approach can be useful in increasing prohormone solubility and vesicles stability, in controlling the in vivo fate of hydrophobic compounds and in avoiding burst release of prohormones from the vesicles. To obtain a stable Cyclosome™, the CDs should have a higher affinity to prohormone molecules compared with liposomal membrane lipids. Cyclosomes prepared by Hi-Tech's double-loading technique are the most advanced targeted prohormone delivery system ever developed because they have a fast onset action with prolonged prohormone release process and the significantly enhanced prohormone-loading capacity.